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The Recombinant Mouse ULBP 1 MULT 1 Protein from R D Systems is derived from NS0 The Recombinant Mouse ULBP 1 MULT 1 Protein has been validated for the following applications Binding Activity
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The Recombinant Mouse ULBP 1 MULT 1 Protein from R D Systems is derived from NS0 The Recombinant Mouse ULBP 1 MULT 1 Protein has been validated for the following applications Binding Activity
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Image Search Results
Journal: Journal of Inflammation Research
Article Title: MULT1-Encoding DNA Alleviates Schistosomiasis-Associated Hepatic Fibrosis via Modulating Cellular Immune Response
doi: 10.2147/JIR.S354224
Figure Lengend Snippet: MULT1 encoding DNA injection alleviates egg granuloma and hepatic fibrosis in mice infected with Schistosoma japonicum . ( A ) Experimental design. Briefly, 6-week-old BALB/c female mice (n=6 per group) were artificially infected with S. japonicum by cutaneous contact with 24 cercariae on a wet cover slip. Administration of 40 μg rMULT1 DNA or vehicle DNA was carried out via hydrodynamic tail vein injection; the process was initialized at 4 weeks post infection and repeated 3 times in 1 month before the mice were anaesthetized and sacrificed at the end point. ( B ) RT-qPCR data and ( C ) sandwich fluorescence immunoassay showing elevated MULT1 expression in p-rMULT1-injected mice compared with control group mice (GFP-ctl) administered vehicle plasmids. ( D ) Representative H&E staining images (left panel, magnification x200) and quantification of mean (±SEM) egg-induced granuloma size in the liver (white circles). ( E ) Representative Masson’s trichrome staining images (left panel, magnification x200) and quantification of mean (±SEM) collagen deposition (right panel). ( F and G ) RT-qPCR showing decrease of ( F ) liver collagen I and ( G ) α-SMA expression. Western blotting assay demonstrating reduced protein concentration of ( H and I ) collagen I, ( H and J ) α-SMA and ( H and K ) TGF-β in the livers of mice administered rMULT1 DNA. Data are representative of 4–6 animals per subgroup and 3 independent experiments. Comparisons were between rMULT1 and GFP-ctl, *P<0.05 and **P<0.01.
Article Snippet: A standard curve was drawn from the MFI of the standard
Techniques: Injection, Infection, Quantitative RT-PCR, Fluorescence, Expressing, Staining, Western Blot, Protein Concentration